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Tuesday, January 31, 2012
Monday, January 30, 2012
EU leaders seek growth as Greece crisis looms (AP)
BRUSSELS ? With another recession looming, European leaders on Monday met in Brussels to discuss ways to stimulate growth and create badly needed jobs, even as they drew up tighter spending limits to avoid a repeat of the crippling debt crisis.
Europe's debt crisis has put the continent and its leaders in an almost impossible situation. While they have to slash their deficits to reassure investors reluctant to lend to them, the debt crisis has also hammered the so-called "real economy," sending unemployment soaring. Many think that only government spending can restart growth.
While the 27 EU leaders meeting in Brussels will focus on walking the fine line between reining in spending and stimulating growth, the elephant in room is Greece.
Greece and its bondholders have come closer to a deal to significantly reduce the country's debt and pave the way for it to receive a much-needed euro130 billion ($170 billion) bailout.
Negotiators for Greece's private creditors said Saturday that a debt-reduction deal could become final within the next week. If the agreement works as planned, it could help Greece avoid a catastrophic default, which would be a blow to Europe's already weak financial system.
But European officials are afraid that even that deal may not be enough to fix Greece's finances, with some blaming Athens for dithering in its austerity promises.
German officials over the weekend proposed that Athens temporarily cede control over tax and spending decisions to a powerful eurozone budget commissioner before it can secure further bailouts.
The idea proved immediately controversial ? both the European Commission and the Greek government refuted it ? to the point that German Chancellor Angela Merkel pulled back on the idea when she arrived in Brussels.
She said Europe had to support Greece in implementing promised austerity and reform measures, "but all that will only work if Greece and all other states discuss this together."
Luxembourg Prime Minister, and head of the group of eurozone finance ministers, Jean-Claude Juncker told reporters as he entered the summit that Greece couldn't be singled out.
"I'm strongly against the idea of imposing the debt commissioner only to Greece, that's just not acceptable" neither for Greece nor the rest of Europe, Juncker said.
The negotiations in Greece are crucial because it is clear that Athens will never be able to pay off all of its debts, especially as austerity measures take their toll on its anemic economy. Martin Schulz, president of the European Parliament, cautioned against punishing Greece too severely.
"Greece needs an economic relaunch today and not in 2016," he told reporters on the sidelines of the summit. "So why not put together a stimulus package today instead of discussing another time a reduction in spending in a country that's in an economic depression?
He said that there are European funds for that kind of stimulus, but unlocking them has always posed a challenge.
The European Commission has proposed to summit leaders that euro82 billion in existing development funds be redirected toward countries in dire need of help to fix their labor markets.
Greece is not alone in facing slow growth and high unemployment. In Spain, for example, unemployment has soared to nearly 23 percent and closed in on 50 percent for those under age 25, leaving more than 5 million people ? or almost one out of every four ? out of work as the country slides toward recession.
Even countries in the so-called European "core" ? which are generally better off ? are suffering. The French government was forced Monday to revise down its growth forecast for the year from 1 percent to just 0.5 percent.
In fact, many now fear that Europe is on the verge of another recession, and leaders gathering Brussels said that spurring growth would be the focus of their talks Monday.
A draft of the summit conclusions, obtained by The Associated Press, proposes reducing barriers to do business across the EU's 27 states and giving better training to young people, who are particularly hard-hit by unemployment.
But it does not contain any new financial stimulus to boost growth, even though turning around Europe's economy would likely require more stimulus from governments, which are currently under pressure to cut ? rather than increase ? spending.
"We have to have balanced budgets and at the same time focus on growth and jobs," said Prime Minister Helle Thorning-Schmidt of Denmark, which holds the rotating presidency of European Council. "It is possible to both at the same time and it is important to understand that these are two sides of the same coin."
The 27 heads of state and government got a taste of the popular frustration with austerity and high unemployment on their way to Monday's summit in a city paralyzed by strikes. Leaders had to fly into the military airport of Beauvechain 20 miles (30 kilometers) outside of Brussels after the city's main airport was shutdown by a 24-hour strike.
Belgium's three main unions joined forces in the walkout to protest national budgetary measures that have in part been imposed on the country by the EU. If the country hadn't met cost-cutting targets, financial sanctions would have been imposed.
Monday's strike has been mirrored in many other member states. Overall, 23 million people are jobless across the EU, 10 percent of the active population.
"Europe has to offer jobs, social protection and perspective for the future. Otherwise it risks losing the support of its citizens," said the strike manifesto of the ACV union.
___
Associated Press writers Don Melvin, Robert Wielaard and Raf Casert contributed to this story.
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Oscar-nominated Glenn Close film opens strong (Reuters)
LOS ANGELES, Jan 29 (TheWrap.com) ? Buoyed by three Oscar nominations, "Albert Nobbs" took a solid $772,730 in its first weekend of wide release.
The Roadside Attractions movie, which earned Glenn Close a best actress nomination, Janet McTeer a best supporting actress nomination and the makeup team a best makeup nomination, opened at 245 locations. Including its Oscar-qualifying numbers in December, the R-rated movie has taken in $822,981.
That's a per-location average of $3,154.
Academy Award nominations were good for a raft of indie films this weekend: The Weinstein Company's "The Artist," nominated for 10 Oscars, including best picture, and "The Iron Lady," nominated for two, each passed $15 million at the box office.
"The Artist," now in its 10th weekend in release, took in $3.3 million at 897 locations. It has grossed $16.7 million. "The Iron Lady" took $3.2 million at 1,244 locations, for a total of $17.5 million. That movie is in its fifth weekend.
And "The Descendants," nominated for five Oscars, including best picture, best director and, for George Clooney, best actor, had its best weekend since its debut 11 weeks ago.
Fox Searchlight expanded the film by 1,441 locations, to 2,001, and saw its numbers increase by 176 percent over last weekend -- to $6.55 million. That's good enough to put it at No. 7 at the overall box office.
"This is a great result for the Academy-nominated movie that has benefited big time from the award season and has become the darling of the general moviegoing audience," Sheila DeLoach, Fox Searchlight's executive VP distribution, told TheWrap. "When you nurture these pictures on this journey and then they break through like this to the general audience, it becomes such a special movie."
It also broke -- or is about to break -- a few records.
With its new total of $58.8 million, "The Descendants" is now the top-grossing independent film released in 2011. Sony Pictures Classics' "Midnight in Paris" -- also a best picture nominee -- had been No. 1 with $56.43 million.
"Descendants" is on the way to becoming director Alexander Payne's top-grossing film. His 2002 "About Schmidt" grossed $65 million, and his 2004 "Sideways" took $71.5 million.
Finally, "The Descendants" is about to surpass "Little Miss Sunshine" as Fox Searchlight's fifth-highest-grossing film ever. The 2006 "Little Miss Sunshine" took $59.9 million.
Another Oscar nominee, Wim Wenders' "Pina," broke the million-dollar mark this week, according to Rentrak.
The 3D film, nominated for best documentary, is about dancer and choreographer Pina Bausch. It expanded from 10 locations to 35, and now has grossed just short of $1.05 million.
Other new indie films opening this weekend include IFC's "Declaration of War," which, according to Rentrak, took $14,400 at six locations, and "An Inconsistent Truth," which grossed $20,282 at one location.
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Sunday, January 29, 2012
Forrester: Apple makes strides into enterprises, users iWork hard for the money
Forrester has announced the results of its latest survey, which encompassed 10,000 enterprise computer users, across 17 countries. It looked at the degree of Apple product adoption in businesses and support for them within IT services. There's plenty to chew on, but here's the big one; over a fifth of those surveyed uses an Apple product for work. This, however, includes workers using their personal devices for work tasks, with 11 percent using their iPhone, 9 percent their iPad and 8 percent working on their Macs. Half of the enterprises included in Forrester's survey plan to increase the number of Macs used by 52 percent, while nearly half of the firms are already issuing Apple PCs to employees, gaining even more traction within IT departments in the US and Western Europe. Unsurprisingly, given its premium pricing, those using Apple gear are more likely to be higher paid, while also (paradoxically) younger and in a senior rank. More specifically, 43 percent of those making over $150,000 a year use an iPhone, iPad or Mac. No cause or effect here, ladies and gents, but we'll be putting in our expense claim for a new set of business iPads very soon.
Forrester: Apple makes strides into enterprises, users iWork hard for the money originally appeared on Engadget on Sat, 28 Jan 2012 09:31:00 EDT. Please see our terms for use of feeds.
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Collaborative research sheds light on new cancer stem cell therapies
ScienceDaily (Jan. 27, 2012) ? A collaborative anti-cancer research jointly conducted by The Hong Kong Polytechnic University (PolyU), Peking University Shenzhen Graduate School and Nevada Cancer Institute has led to the development of a novel class of chemical inhibitors that specifically target cancer cells with pluripotency.
This cutting-edge research has combined the effort of three research teams including one led by Dr Tao Ye (??), Associate Professor of PolyU's Department of Applied Biology and Chemical Technology. This breakthrough may help the selective removal of cancer stem cells and potentially provide a novel strategy to eradicate cancers.
Cancer is a major cause of human death in China and all around the world. It is difficult to treat cause of the existence of cancer initiating cells/cancer stem cells. Although they exist in very few in numbers, cancer stem cells (CSCs) can proliferate and self-renew, and are pluripotent and multipotent, which have the capability to differentiate into various more heterogeneous cancer cells that constitute the entire tumor mass. As stem cells, they are more resistant to most conventional cancer therapies such as chemotherapy or radiotherapy due to their differences in the cell cycle regulation and DNA repair processes. They also act as the source for metastasis and recurring drug resistant cancers after conventional cancer therapy. Currently, there are no chemical inhibitors or other agents that can specifically and selectively target cancer stem cells. The development of compounds that target cancer stem cells is an unmet medical demand for the eradication of malignant cancers.
According to Dr Ye, the potential clinical applications of new LSD1 inhibitors include the following:
(1) They can be used to treat malignant germ cell tumors such as teratoma/teratocarcinomas, embryonic carcinomas, seminomas, choriocarcinomas, and tumors of yolk sac. These tumors are usually treated by surgery or cis-platinum, but after initial treatment, these tumors always become resistant to platinum drugs. So far, the LSD1 inhibitors are highly effective towards these pluriptont cancers with stem cell properties.
(2) The LSD1 inhibitors may also be used to remove teratomas/embryonic carcinomas during stem cell-based therapy. One major problem in stem/iPS cell-based therapy is the formation of embryonic carcinomas, teratomas, or teratocarcinomas by incomplete differentiation of ES/iPS cells in the organs of recipients.? Because LSD1 selectively inhibit these pluripotent embryonic carcinomas, teratomas, or teratocarcinomas, LSD1 inhibitors may help ensure the successful application of stem cell-based therapy.
(3) More importantly, since teratomas/embryonic carcinomas are pluripotent cancer stem cells, researchers will probe whether cancer stem cells of other types of major organ-specific cancers such as breast, ovarian, lung, and brain cancers are sensitive to these LSD1 inhibitors. Further studies indicated that LSD1 inhibitors can also be used to inhibit many cancer stem cell-like cells such as breast and ovarian cancers.
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The above story is reprinted from materials provided by The Hong Kong Polytechnic University, via ResearchSEA.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal References:
- Felix Cheung. Cancer biology: Ridding the seeds of evil. Nature China, 2012; DOI: 10.1038/nchina.2012.1
- J. Wang, F. Lu, Q. Ren, H. Sun, Z. Xu, R. Lan, Y. Liu, D. Ward, J. Quan, T. Ye, H. Zhang. Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties. Cancer Research, 2011; 71 (23): 7238 DOI: 10.1158/0008-5472.CAN-11-0896
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://www.sciencedaily.com/releases/2012/01/120127135444.htm
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Saturday, January 28, 2012
Twitter to begin 'reactively' censoring tweets in specific countries, still no love for China
This may seem like some form of censorship taking over Twitter, but the company only mentioned those of "historical or cultural reasons" like the ban of pro-Nazi content in France and Germany; so it's not clear whether Twitter will also handle similarly with tweets that potentially lead to events such as the UK riots last year. Even though Twitter didn't elaborate further for Reuters, there is one reassuring line in the post:
One such country is most likely China, and back at AsiaD in October, Twitter CEO Jack Dorsey told us that there's simply no way for his company to work with the Chinese government (you can watch him answering us at 38:17 in the video -- courtesy of All Things D -- after the break):"Some [countries] differ so much from our ideas that we will not be able to exist there."
There are obviously many factors that add up to this sour relationship, but the contradiction between China's strict internet monitoring policy and Twitter's core values is most likely the biggest obstacle. And of course, the Chinese government would favor its home-grown tech properties, anyway. That said, several months ago, one of the country's largest microblogging services Sina Weibo was criticized by the authorities for not censoring fast enough, so it's obvious that it'd be even trickier to work with a foreign company that sees things differently. Things are unlikely to change any time soon, or ever, unless China relaxes its policy."The unfortunate fact is we're just not allowed to compete in this market, and that's not up to us to change. The person to ask is trade experts between both governments, but at the end of the day we can't compete. They (Chinese microblogging platforms) can compete in our markets, and we're certainly interested in what that means for us... We would love to have a strong Twitter in China, but we'd need to be allowed to do that."
Twitter to begin 'reactively' censoring tweets in specific countries, still no love for China originally appeared on Engadget on Fri, 27 Jan 2012 04:20:00 EDT. Please see our terms for use of feeds.
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Demi Moore 911 Call: 'She's Been Having Some Issues'
'She's shaking, convulsing, burning up,' one caller says the night of Moore's hospitalization.
By Jocelyn Vena
Demi Moore
Photo: Jason Kempin/ Getty Images
In the 911 call made the night of Demi Moore's hospitalization, a female caller is heard describing the events that led to the actress' Monday health scare.
Describing Moore's condition as "semiconscious, barely," the caller told the 911 operator, "She smoked something. It's not marijuana, but it's similar to it. It's similar to incense. She seems to be having convulsions of some sort."
The first caller then passed the phone to another woman, who added, "She's shaking, convulsing, burning up. I'm taking cold water and putting it on her back because she's burning up. I don't know what would have made her do it."
Demi's hospitalization has soon-to-be ex-husband Ashton Kutcher "deeply concerned."
There appeared to be several other people present at the time of the call, as they all frantically tried to keep the actress afloat. When asked if it was common for Moore to react in this way, one caller said, "There has been some stuff recently that we're just finding out." Another caller added: "She's been having some issues lately with some other stuff, so I don't know what she's been taking or not."
As the seven-minute phone call wrapped up, the paramedics arrived to the residence. On Tuesday, Moore's rep said she had been hospitalized due to "exhaustion"; however, there has been speculation that she had been inhaling nitrous oxide at the time of the incident.
Moore's health scare caps a rough patch for the actress.
Sources told E! News that her three daughters are doing fine. Rumer, 23, visited her mother several times at the hospital before she was discharged earlier this week. Tallulah, 17, is with her dad, Bruce Willis. "She's doing great," the source told E! "Her grandmother [Bruce's mom] is also there with her." Moore's other daughter, 20-year-old Scout, goes to Brown University in Rhode Island and reportedly hasn't been home since the incident.
On Friday (January 27), news broke that Mary Louise-Parker has replaced Moore in the "Lovelace" film, currently filming in Los Angeles.
Related PhotosSource: http://www.mtv.com/news/articles/1678052/demi-moore-911-call.jhtml
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